Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) Antibody (HRP)

Este producto es parte de GAPDH - Glyceraldehyde-3-phosphate dehydrogenase
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169€ (20 µg)

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935106861
info@markelab.com
name
Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) Antibody (HRP)
category
Primary Antibodies
provider
Abbexa
reference
abx109085
tested applications
ELISA

Description

GAPDH Antibody (HRP) is a Rabbit Polyclonal antibody against GAPDH conjugated to HRP.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH)
Host
Rabbit
Reactivity
Chicken
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
HRP
Isotype
IgG
Purity
> 95%
Purification
Purified by Protein G.
Size 1
20 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
1 mg
Form
Liquid
Tested Applications
ELISA
Buffer
0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P00356
Gene ID
374193
Alias
GAPDH, GAPD, G3PD, HEL-S-162eP,Peptidyl-cysteine S-nitrosylase GAPDH
Background
Antibody anti-GAPDH
Status
RUO

Descripción

Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a multifunctional enzyme predominantly involved in glycolysis, catalyzing the oxidative phosphorylation of glyceraldehyde-3-phosphate to 1,3-bisphosphoglycerate using NAD+ as a cofactor. Beyond its metabolic role, GAPDH participates in various non-metabolic processes, including transcriptional regulation, DNA repair, and cell apoptosis. Its involvement in oxidative stress response and as a target for S-nitrosylation connects it to neurodegenerative diseases such as Alzheimer's and Parkinson's. Furthermore, GAPDH can translocate to the nucleus under stress conditions, influencing apoptotic pathways.

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