Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) Antibody

Pida mas información
935106861
info@markelab.com
Precio
221€ (50 µg)
Antibody anti-GAPDH
proveedor
Abbexareference
abx159514Tested Applications
ELISA, WBreactivity
Human, Mouse, Rat, Monkey, Dog, Chicken, Hamster, Rabbit, Pig, Sheepstatus
RUOclonality
MonoclonalDescripción
GAPDH Antibody is a Mouse Monoclonal against GAPDH.
Background
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a multifunctional enzyme predominantly involved in glycolysis, catalyzing the oxidative phosphorylation of glyceraldehyde-3-phosphate to 1,3-bisphosphoglycerate using NAD+ as a cofactor. Beyond its metabolic role, GAPDH participates in various non-metabolic processes, including transcriptional regulation, DNA repair, and cell apoptosis. Its involvement in oxidative stress response and as a target for S-nitrosylation connects it to neurodegenerative diseases such as Alzheimer's and Parkinson's. Furthermore, GAPDH can translocate to the nucleus under stress conditions, influencing apoptotic pathways.
Características del producto
category
Primary Antibodies
clonality
Monoclonal
reactivity
Human, Mouse, Rat, Monkey, Dog, Chicken, Hamster, Rabbit, Pig, Sheep
immunogen target
Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH)
host
Mouse
isotype
IgG
conjugation
Unconjugated
form
Liquid
tested applications
ELISA, WB
purification
¥
recommended dilution
WB: 1/500 - 1/5000. Optimal dilutions/concentrations should be determined by the end user.
buffer
PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
size 1
50 µg
size 2
100 µg
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
GAPDH
dry ice
No
availability
Shipped within 5-10 working days.
alias
GAPDH, GAPD, G3PD, HEL-S-162eP,Peptidyl-cysteine S-nitrosylase GAPDH
uniprot id
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