Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) Antibody

Este producto es parte de GAPDH - Glyceraldehyde-3-phosphate dehydrogenase
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637€ (100 µl)

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935106861
info@markelab.com
name
Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx112787
tested applications
ELISA, WB, IHC, IF/ICC

Description

GAPDH Antibody is a Rabbit Polyclonal antibody against GAPDH.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH)
Host
Rabbit
Reactivity
Human, Mouse, Rat, Pig
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Antigen Affinity Chromatography.
Size 1
100 µl
Form
Liquid
Tested Applications
ELISA, WB, IHC, IF/ICC
Buffer
PBS, pH 7.3, containing 0.1% Sodium Azide and 50% Glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P04406
Gene ID
2597
NCBI Accession
NP_001243728.1, NM_001256799.2, NP_001276674.1, NM_001289745.1
OMIM
138400
Alias
GAPDH, GAPD, G3PD, HEL-S-162eP,Peptidyl-cysteine S-nitrosylase GAPDH
Background
Antibody anti-GAPDH
Status
RUO

Descripción

Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a multifunctional enzyme predominantly involved in glycolysis, catalyzing the oxidative phosphorylation of glyceraldehyde-3-phosphate to 1,3-bisphosphoglycerate using NAD+ as a cofactor. Beyond its metabolic role, GAPDH participates in various non-metabolic processes, including transcriptional regulation, DNA repair, and cell apoptosis. Its involvement in oxidative stress response and as a target for S-nitrosylation connects it to neurodegenerative diseases such as Alzheimer's and Parkinson's. Furthermore, GAPDH can translocate to the nucleus under stress conditions, influencing apoptotic pathways.

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