Gastrin Releasing Peptide (GRP) Antibody (HRP)
169€ (20 µg)
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Name
Gastrin Releasing Peptide (GRP) Antibody (HRP)
Category
Primary Antibodies
Provider
Abbexa
Reference
abx107871
Tested Applications
ELISA
Description
Gastrin-releasing peptide Antibody (HRP) is a Rabbit Polyclonal antibody against Gastrin-releasing peptide conjugated to HRP.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Gastrin Releasing Peptide (GRP) Immunogen: Recombinant human Gastrin-releasing peptide protein (31-98AA). |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | HRP |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P07492 |
| Gene ID | 2922 |
| NCBI Accession | NP_001012530.1, NM_001012512.2 |
| OMIM | 137260 |
| Alias | BN,GRP-10,proGRP,preproGRP |
| Background | Antibody anti-GRP |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
GRP is a neuropeptide that acts as the mammalian equivalent of bombesin, a peptide involved in stimulating the release of gastrin and other gastrointestinal hormones GRP is primarily secreted by nerve endings in the gastrointestinal tract and pancreas, where it regulates gastric acid secretion, gastrointestinal motility, and nutrient absorption It exerts its effects by binding to the gastrin-releasing peptide receptor (GRPR), a G-protein-coupled receptor GRP plays an important role in cell proliferation, wound healing, and neural signaling in the central nervous system Dysregulated GRP expression is associated with the pathogenesis of cancers, particularly small cell lung cancer (SCLC) and prostate cancer, where it promotes tumor cell growth and metastasis GRP and its receptor are also implicated in inflammatory processes and neurological conditions, making them potential targets for cancer therapy and gastrointestinal disorders
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