Fibroblast Growth Factor Receptor 2 Phospho-Tyr769 (FGFR2 pY769) Antibody

Este producto es parte de FGFR2 - fibroblast growth factor receptor 2
Product Graph
351€ (50 µl)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
Fibroblast Growth Factor Receptor 2 Phospho-Tyr769 (FGFR2 pY769) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx215352
tested applications
WB, IHC

Description

FGFR2 (pY769) Antibody is a Rabbit Polyclonal against FGFR2 (pY769).

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Fibroblast Growth Factor Receptor 2 Phospho-Tyr769 (FGFR2 pY769)
Host
Rabbit
Reactivity
Human, Mouse
Recommended Dilution
WB: 1/1000, IHC-P: 1/200. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Purification
Purified by antigen affinity chromatography.
Size 1
50 µl
Size 2
100 µl
Form
Liquid
Tested Applications
WB, IHC
Buffer
PBS, pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P21802
Gene ID
2263
Alias
BEK,JWS,BBDS,CEK3,CFD1,ECT1,KGFR,TK14,TK25,BFR-1,CD332,K-SAM,Keratinocyte growth factor receptor,FGFR-2
Background
Antibody anti-FGFR2
Status
RUO
Note
Concentration: 1 mg/ml - 

Descripción

Related Products

EH3060

Human FGFR2 (Fibroblast Growth Factor Receptor 2) ELISA Kit

Ver Producto
FNab03102

FGFR2 antibody

Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, differentiation, migration and apoptosis, and in the regulation of embryonic development. Required for normal embryonic patterning, trophoblast function, limb bud development, lung morphogenesis, osteogenesis and skin development. Plays an essential role in the regulation of osteoblast differentiation, proliferation and apoptosis, and is required for normal skeleton development. Promotes cell proliferation in keratinocytes and immature osteoblasts, but promotes apoptosis in differentiated osteoblasts. Phosphorylates PLCG1, FRS2 and PAK4. Ligand binding leads to the activation of several signaling cascades. Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate. Phosphorylation of FRS2 triggers recruitment of GRB2, GAB1, PIK3R1 and SOS1, and mediates activation of RAS, MAPK1/ERK2, MAPK3/ERK1 and the MAP kinase signaling pathway, as well as of the AKT1 signaling pathway. FGFR2 signaling is down-regulated by ubiquitination, internalization and degradation. Mutations that lead to constitutive kinase activation or impair normal FGFR2 maturation, internalization and degradation lead to aberrant signaling. Over-expressed FGFR2 promotes activation of STAT1.

Ver Producto
FNab09802

Phospho-FGFR2 (ser782) Antibody

Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, differentiation, migration and apoptosis, and in the regulation of embryonic development.FGFR2(Phospho-Ser782) Antibody detects endogenous levels of FGFR2 only when phosphorylated at Ser782.

Ver Producto