FGFR2 is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member is a high-affinity receptor for acidic, basic and/or keratinocyte growth factor, depending on the isoform. Mutations in FGFR2 gene are associated with Crouzon syndrome, Pfeiffer syndrome, Craniosynostosis, Apert syndrome, Jackson-Weiss syndrome, Beare-Stevenson cutis gyrata syndrome, Saethre-Chotzen syndrome, and syndromic craniosynostosis.
Primary Antibodies
Polyclonal
Human
Fibroblast Growth Factor Receptor 2 (FGFR2)
Rabbit
Unconjugated
Liquid
ELISA, WB, IHC, IF/ICC, FCM
Purified Rabbit Polyclonal Antibody.
PBS containing 0.09% sodium azide.
80 µl
400 µl
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
FGFR2
No
Shipped within 5-10 working days.
BEK,JWS,BBDS,CEK3,CFD1,ECT1,KGFR,TK14,TK25,BFR-1,CD332,K-SAM,Keratinocyte growth factor receptor,FGFR-2
This product is for research use only.
Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in ...
Precio a consultar
Ver másTyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in ...
Precio a consultar
Ver másFGFR2 Antibody is a Rabbit Polyclonal antibody against FGFR2. The protein encoded by this gene is a member of the fibrob...
175€ (20 µl)
Ver más