Fc receptor-like protein 3 (FCRL3) Antibody (Biotin)
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935106861
info@markelab.com
Precio
169€ (20 µg)
Antibody anti-FCRL3
proveedor
Abbexareference
abx348574Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
PolyclonalDescripción
Fc receptor-like protein 3 (FCRL3) Antibody (Biotin) is a Rabbit Polyclonal antibody conjugated to Biotin for the detection of Human FCRL3.
Background
Fc Receptor Like 3 (FCRL3) is expressed on B cells, regulatory T cells, and some natural killer cells, functioning as an immune checkpoint molecule. The presence of ITIMs in its structure supports its inhibitory role in immune regulation, particularly in dampening autoimmunity. FCRL3 polymorphisms have been linked to autoimmune diseases such as rheumatoid arthritis and type 1 diabetes, where genetic variants contribute to increased susceptibility. Collectively, the FCRL family represents a critical set of regulators for immune cell function, offering potential therapeutic targets for autoimmune disorders and B cell-related malignancies.
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human
immunogen target
Fc receptor-like protein 3 (FCRL3)
host
Rabbit
isotype
IgG
conjugation
Biotin
form
Liquid
tested applications
ELISA
purity
> 95%
purification
Purified by Protein G chromatography.
recommended dilution
Optimal dilutions/concentrations should be determined by the end user.
buffer
0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% glycerol.
size 1
20 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
1 mg
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
FCRL3
dry ice
No
availability
Shipped within 5-10 working days.
alias
Fc receptor-like protein 3,MAIA,FCRH3,IFGP3,IRTA3,SPAP2,CD307c,Fc receptor homolog 3,IFGP family protein 3,Hifgp3
uniprot id
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