Fc Receptor-Like Protein 1 (FCRL1) Antibody
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Description
Fc Receptor-Like Protein 1 (FCRL1) Antibody is a Rabbit Polyclonal antibody against Fc Receptor-Like Protein 1 (FCRL1).
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Fc Receptor-Like Protein 1 (FCRL1) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Purification | Purified by affinity chromatography using epitope-specific immunogen. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q96LA6 |
| Gene ID | 115350 |
| Alias | Fc receptor-like protein 1FcR-like protein 1,FcRL1,Fc receptor homolog 1,FCRH1,IFGP1,IRTA5,CD307a |
| Background | Antibody anti-FCRL1 |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
Fc Receptor Like 1 (FCRL1) is a transmembrane protein expressed primarily on B cells and is a member of the immunoglobulin superfamily. It plays a role in regulating B cell activation and immune responses. The cytoplasmic domain of FCRL1 contains both immunoreceptor tyrosine-based activation motifs (ITAMs) and immunoreceptor tyrosine-based inhibitory motifs (ITIMs), suggesting it can transmit both activating and inhibitory signals. Dysregulation of FCRL1 expression has been associated with autoimmune conditions like systemic lupus erythematosus (SLE), indicating its importance in immune tolerance and balance.
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