Fc Fragment of IgG Low Affinity IIIa Receptor (FCGR3A) Antibody (FITC)

Este producto es parte de FCGR3A - Fc gamma receptor IIIa
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702€ (100 µg)

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935106861
info@markelab.com
name
Fc Fragment of IgG Low Affinity IIIa Receptor (FCGR3A) Antibody (FITC)
category
Primary Antibodies
provider
Abbexa
reference
abx413583
tested applications
FCM

Description

Low Affinity Immunoglobulin Gamma Fc Region Receptor III-B (CD16) Antibody (FITC) is a Mouse Monoclonal antibody against Low Affinity Immunoglobulin Gamma Fc Region Receptor III-B (CD16).

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Fc Fragment of IgG Low Affinity IIIa Receptor (FCGR3A)
Host
Mouse
Reactivity
Pig
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Clonality
Monoclonal
Conjugation
FITC
Isotype
IgG1
Purification
Purified
Size 1
100 µg
Form
Liquid
Tested Applications
FCM
Buffer
PBS, 1% BSA. Contains sodium azide.
Availability
Shipped within 3-7 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q28942
Alias
CD16,FCG3,CD16A,FCGR3,IGFR3,IMD20,FCR-10,FCRIII,CD16-II,FCGRIII,FCRIIIA,FcGRIIIA,Low affinity immunoglobulin gamma Fc region receptor III-A,IgG Fc receptor III-A,IgG Fc receptor III-2
Background
Antibody anti-FCGR3A
Status
RUO
Note
Concentration: 0.1 mg/ml - 

Descripción

FCGR3A, or Fc gamma receptor IIIa, is a membrane-bound protein that plays a crucial role in the immune system, specifically in mediating immune responses through the recognition of the Fc region of IgG antibodies. This receptor is primarily expressed on the surface of natural killer (NK) cells, macrophages, monocytes, and dendritic cells, where it facilitates antibody-dependent cellular cytotoxicity (ADCC) and other immune responses. It is part of the broader family of Fc gamma receptors (FcγRs), which are responsible for binding to the Fc region of IgG antibodies, thereby linking humoral and cellular immunity. FCGR3A has garnered considerable attention in immunology due to its role in recognizing and responding to immune complexes, infected cells, and tumor cells coated with IgG antibodies. Variations in the gene encoding FCGR3A have been implicated in differential responses to infections, autoimmune diseases, and cancer therapies

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