Fc Fragment of IgG Low Affinity IIIa Receptor (FCGR3A) Antibody

Este producto es parte de FCGR3A - Fc gamma receptor IIIa
Fc Fragment of IgG Low Affinity IIIa Receptor (FCGR3A) Antibody
357.5€ (100 µg)

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Name
Fc Fragment of IgG Low Affinity IIIa Receptor (FCGR3A) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx145179
Tested Applications
ELISA, WB

Description

FCGR3A Antibody is a Rabbit Polyclonal against FCGR3A.

Documentos del producto

Instrucciones
Data sheet
Descargar

Especificaciones del producto

Category
Primary Antibodies
Immunogen Target
Target: Fc Fragment of IgG Low Affinity IIIa Receptor (FCGR3A)
Immunogen: Recombinant fragment corresponding to 49-206 AA of human FCGR3A.
Host
Rabbit
Reactivity
Human
Assay Type
Concentration: Lyophilized form: Not applicable.  After reconstitution: 1 mg/ml.
Recommended Dilution
ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
Observed MW: 30 kDa
Purification
Purified by antigen affinity column chromatography.
Size 1
100 µg
Size 2
1 mg
Form
Lyophilized
Tested Applications
ELISA, WB
Buffer
Prior to lyophilization: 1% BSA and 0.02% NaN3.
Availability
Shipped within 7-15 working days.
Storage
Store at -20 °C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
NCBI Accession
BC033678
Alias
CD16,FCG3,CD16A,FCGR3,IGFR3,IMD20,FCR-10,FCRIII,CD16-II,FCGRIII,FCRIIIA,FcGRIIIA,Low affinity immunoglobulin gamma Fc region receptor III-A,IgG Fc receptor III-A,IgG Fc receptor III-2
Background
Antibody anti-FCGR3A
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

Background

FCGR3A, or Fc gamma receptor IIIa, is a membrane-bound protein that plays a crucial role in the immune system, specifically in mediating immune responses through the recognition of the Fc region of IgG antibodies. This receptor is primarily expressed on the surface of natural killer (NK) cells, macrophages, monocytes, and dendritic cells, where it facilitates antibody-dependent cellular cytotoxicity (ADCC) and other immune responses. It is part of the broader family of Fc gamma receptors (FcγRs), which are responsible for binding to the Fc region of IgG antibodies, thereby linking humoral and cellular immunity. FCGR3A has garnered considerable attention in immunology due to its role in recognizing and responding to immune complexes, infected cells, and tumor cells coated with IgG antibodies. Variations in the gene encoding FCGR3A have been implicated in differential responses to infections, autoimmune diseases, and cancer therapies

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