Exonuclease 3'-5' Domain Containing Protein 2 (EXD2) Antibody (FITC)
169€ (20 µg)
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935106861
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name
Exonuclease 3'-5' Domain Containing Protein 2 (EXD2) Antibody (FITC)
category
Primary Antibodies
provider
Abbexa
reference
abx313857
Description
EXD2 Antibody (FITC) is a Rabbit Polyclonal against EXD2 conjugated to FITC.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Exonuclease 3'-5' Domain Containing Protein 2 (EXD2) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | FITC |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9NVH0 |
| Gene ID | 55218 |
| NCBI Accession | NP_001180289.1, NM_001193360.1 |
| OMIM | 616940 |
| Background | Antibody anti-EXD2 |
| Status | RUO |
Descripción
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Exonuclease required for double-strand breaks resection and efficient homologous recombination. Plays a key role in controlling the initial steps of chromosomal break repair, it is recruited to chromatin in a damage-dependent manner and functionally interacts with the MRN complex to accelerate resection through its 3'-5' exonuclease activity, which efficiently processes double-stranded DNA substrates containing nicks.
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