Exonuclease 3'-5' Domain Containing Protein 2 (EXD2) Antibody
364€ (100 µg)
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935106861
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name
Exonuclease 3'-5' Domain Containing Protein 2 (EXD2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx232890
tested applications
ELISA, WB, IHC, IF/ICC, IP
Description
EXD2 Antibody is a Rabbit Polyclonal against EXD2.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Exonuclease 3'-5' Domain Containing Protein 2 (EXD2) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1/500 - 1/2000, IHC: 1/20 - 1/200, IF/ICC: 1/20 - 1/200, IP: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC, IF/ICC, IP |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9NVH0 |
| Gene ID | 55218 |
| NCBI Accession | NP_001180289.1, NM_001193360.1 |
| OMIM | 616940 |
| Background | Antibody anti-EXD2 |
| Status | RUO |
| Note | Concentration: 2 mg/ml - Validity: 12 months. |
Descripción
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Exonuclease required for double-strand breaks resection and efficient homologous recombination. Plays a key role in controlling the initial steps of chromosomal break repair, it is recruited to chromatin in a damage-dependent manner and functionally interacts with the MRN complex to accelerate resection through its 3'-5' exonuclease activity, which efficiently processes double-stranded DNA substrates containing nicks.
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EXD2 Antibody (HRP) is a Rabbit Polyclonal against EXD2 conjugated to HRP.
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