EXD2 antibody

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935106861
info@markelab.com
name
EXD2 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab02890
tested applications
ELISA, WB, IF, IHC, IP

Description

Exonuclease required for double-strand breaks resection and efficient homologous recombination. Plays a key role in controlling the initial steps of chromosomal break repair, it is recruited to chromatin in a damage-dependent manner and functionally interacts with the MRN complex to accelerate resection through its 3'-5' exonuclease activity, which efficiently processes double-stranded DNA substrates containing nicks.

Documents del producto

Instrucciones
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Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
exonuclease 3'-5' domain containing 2 (EXD2)
Host
Rabbit
Reactivity
Human, Mouse, Rat
Recommended Dilution
WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200
Clonality
polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
56 kDa
Purity
≥95% as determined by SDS-PAGE
Purification
Immunogen affinity purified
Size 1
100µg
Form
liquid
Tested Applications
ELISA, WB, IF, IHC, IP
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
UniProt ID
Q9NVH0
Gene ID
55218
Alias
Exonuclease 3'-5' domain-containing protein 2,3'-5' exoribonuclease EXD2,Exonuclease 3'-5' domain-like-containing protein 2,EXD2,C14orf114,EXDL2
Background
Antibody anti-EXD2
Status
RUO
Note
Mol. Weight 56 kDa

Descripción

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