Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1) Antibody
312€ (60 µl)
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Name
Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx001160
Tested Applications
IHC
Description
EIF4EBP1 Antibody is a Rabbit Polyclonal antibody against EIF4EBP1. This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1) Immunogen: A synthetic peptide corresponding to human EIF4EBP1 |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Assay Type | Concentration: 1 mg/ml |
| Recommended Dilution | IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Calculated MW: 12 kDa |
| Purification | Purified by affinity chromatography. |
| Size 1 | 60 µl |
| Size 2 | 120 µl |
| Size 3 | 200 µl |
| Form | Liquid |
| Tested Applications | IHC |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q13541 |
| Gene ID | 1978 |
| NCBI Accession | NP_004086.1 |
| Alias | 4E-BP1,4EBP1,BP-1,PHAS-I |
| Background | Antibody anti-EIF4EBP1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
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