EIF4EBP1 (pT45) Antibody
208€ (20 µl)
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Name
EIF4EBP1 (pT45) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx000271
Tested Applications
WB
Description
EIF4EBP1 (pT45) Antibody is a Rabbit Polyclonal antibody against EIF4EBP1 (pT45). This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: EIF4EBP1 (pT45) Immunogen: A phospho specific peptide corresponding to residues surrounding T45 of human Phospho-eIF4EBP1-T45 |
| Host | Rabbit |
| Reactivity | Human |
| Assay Type | Concentration: > 0.2 mg/ml |
| Recommended Dilution | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Calculated MW: 13 kDa Observed MW: 18 kDa |
| Purification | Purified by affinity chromatography. |
| Size 1 | 20 µl |
| Size 2 | 100 µl |
| Size 3 | 2 × 100 µl |
| Form | Liquid |
| Tested Applications | WB |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q13541 |
| Gene ID | 1978 |
| Alias | 4E-BP1,4EBP1,BP-1,PHAS-I |
| Background | Antibody anti-EIF4EBP1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
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