EIF4EBP1 (pT36) Antibody

EIF4EBP1 (pT36) Antibody
208€ (20 µl)

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Name
EIF4EBP1 (pT36) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx000392
Tested Applications
ELISA, WB

Description

EIF4EBP1 (pT36) Antibody is a Rabbit Polyclonal antibody against EIF4EBP1 (pT36). This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.

Documentos del producto

Instrucciones
Data sheet
Descargar

Especificaciones del producto

Category
Primary Antibodies
Immunogen Target
Target: EIF4EBP1 (pT36)
Immunogen: A synthetic phosphorylated peptide around T36 of human eIF4EBP1.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Assay Type
Concentration: > 0.2 mg/ml
Recommended Dilution
ELISA: 1 µg/ml, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
Calculated MW: 13 kDa  Observed MW: 20 kDa
Purification
Purified by affinity chromatography.
Size 1
20 µl
Size 2
100 µl
Size 3
2 × 100 µl
Form
Liquid
Tested Applications
ELISA, WB
Buffer
PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q13541
Gene ID
1978
NCBI Accession
NP_004086.1
Alias
4E-BP1,4EBP1,BP-1,PHAS-I
Background
Antibody anti-EIF4EBP1
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

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