Eukaryotic Translation Elongation Factor 1 Gamma (EEF1G) Antibody
52€ (10 µg)
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935106861
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name
Eukaryotic Translation Elongation Factor 1 Gamma (EEF1G) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx014450
tested applications
ELISA, WB
Description
Rabbit polyclonal antibody against EEF1G protein. Immunogen region is Internal.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Eukaryotic Translation Elongation Factor 1 Gamma (EEF1G) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1/500 - 1/3000, ELISA: 1/20000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. |
| Size 1 | 10 µg |
| Size 2 | 100 µg |
| Size 3 | 200 µg |
| Size 4 | 300 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS (without Mg<sup>2+</sup> and Ca<sup>2+</sup>), pH 7.4, 150 mM NaCl, 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P26641 |
| Alias | EF1G,EF-1-gamma,eEF-1B gamma |
| Background | Antibody anti-EEF1G |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
EEF1G is a structural subunit of the eukaryotic elongation factor 1 (eEF1) complex, which mediates the delivery of aminoacyl-tRNA to the ribosome during protein elongation. Unlike other subunits, EEF1G plays a scaffolding role, stabilizing the eEF1 complex and enabling interactions with additional proteins involved in translation, signal transduction, and cellular metabolism. EEF1G is also implicated in translational regulation under stress conditions, where it interacts with molecular chaperones and other protein complexes to maintain translation fidelity and protein stability. Elevated expression of EEF1G has been associated with cancer progression, particularly in breast, colorectal, and liver cancers, where it contributes to enhanced protein synthesis, cell proliferation, and survival. Its role as a scaffold protein highlights its significance in coordinating protein synthesis and cellular signaling pathways critical for growth and stress adaptation.
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