EEF1G antibody
Contáctenos para saber el precio
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
EEF1G antibody
category
Primary Antibodies
provider
FineTest
reference
FNab02650
tested applications
ELISA, WB, IHC
Description
This gene encodes a subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This subunit contains an N-terminal glutathione transferase domain, which may be involved in regulating the assembly of multisubunit complexes containing this elongation factor and aminoacyl-tRNA synthetases.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | eukaryotic translation elongation factor 1 gamma (EEF1G) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500 - 1:2000; IHC: 1:50 - 1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 50 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P26641 |
| Gene ID | 1937 |
| Alias | EF1G,EF-1-gamma,eEF-1B gamma |
| Background | Antibody anti-EEF1G |
| Status | RUO |
| Note | Mol. Weight 50 kDa |
Descripción
EEF1G is a structural subunit of the eukaryotic elongation factor 1 (eEF1) complex, which mediates the delivery of aminoacyl-tRNA to the ribosome during protein elongation. Unlike other subunits, EEF1G plays a scaffolding role, stabilizing the eEF1 complex and enabling interactions with additional proteins involved in translation, signal transduction, and cellular metabolism. EEF1G is also implicated in translational regulation under stress conditions, where it interacts with molecular chaperones and other protein complexes to maintain translation fidelity and protein stability. Elevated expression of EEF1G has been associated with cancer progression, particularly in breast, colorectal, and liver cancers, where it contributes to enhanced protein synthesis, cell proliferation, and survival. Its role as a scaffold protein highlights its significance in coordinating protein synthesis and cellular signaling pathways critical for growth and stress adaptation.
Related Products
EEF1G antibody
This gene encodes a subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This subunit contains an N-terminal glutathione transferase domain, which may be involved in regulating the assembly of multisubunit complexes containing this elongation factor and aminoacyl-tRNA synthetases.
Ver Producto
Recombinant Human EEF1G
Ver Producto
Eukaryotic Translation Elongation Factor 1 Gamma (EEF1G) Antibody
Rabbit polyclonal antibody against EEF1G protein. Immunogen region is Internal.
Ver Producto