Eukaryotic Translation Elongation Factor 1 Epsilon 1 (EEF1E1) Antibody
637€ (100 µl)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Eukaryotic Translation Elongation Factor 1 Epsilon 1 (EEF1E1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx112352
tested applications
ELISA, WB, IHC
Description
Eukaryotic Translation Elongation Factor 1 Epsilon 1 Antibody is a Rabbit Polyclonal antibody against Eukaryotic Translation Elongation Factor 1 Epsilon 1.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Eukaryotic Translation Elongation Factor 1 Epsilon 1 (EEF1E1) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS, pH 7.3, containing 0.1% Sodium Azide and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O43324 |
| Gene ID | 9521 |
| NCBI Accession | NP_001129122.1, NM_001135650.1, NP_004271.1, NM_004280.4 |
| OMIM | 609206 |
| Alias | AIMP3, P18,EEF1E1 |
| Background | Antibody anti-EEF1E1 |
| Status | RUO |
Descripción
EEF1E1 is a subunit of the eukaryotic elongation factor 1 (eEF1) complex, which plays a critical role in protein synthesis by facilitating the recruitment of aminoacyl-tRNA to the ribosome during elongation. EEF1E1 functions as a structural component, stabilizing the interaction between other subunits, such as EEF1A and EEF1B, within the eEF1 complex. It is also involved in regulating the exchange of GDP for GTP on EEF1A, a critical step in elongation cycle progression. EEF1E1 is expressed ubiquitously, reflecting its essential role in maintaining efficient protein translation in all cells. Dysregulation of EEF1E1 has been linked to cancer progression, where increased protein synthesis supports tumor growth and proliferation. It is also implicated in neurodegenerative diseases, where disruptions in protein homeostasis and elongation factor function are contributing factors. Further studies are needed to explore its broader roles in translational control and disease pathology.
Related Products
Recombinant Human EEF1E1
Ver Producto
Eukaryotic Translation Elongation Factor 1 Epsilon 1 (EEF1E1) Antibody
Rabbit Polyclonal against the EEF1E1 protein.
Ver Producto