ER Lipid Raft Associated 2 (ERLIN2) Antibody
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Description
ERLIN2 Antibody is a Rabbit Polyclonal Antibody against ERLIN2.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: ER Lipid Raft Associated 2 (ERLIN2) Immunogen: Recombinant fusion protein corresponding to human ERLIN2 |
| Host | Rabbit |
| Reactivity | Human |
| Assay Type | Concentration: 1 mg/ml |
| Recommended Dilution | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Calculated MW: 16 kDa/22 kDa/37 kDa Observed MW: 38 kDa |
| Purification | Purified by affinity chromatography. |
| Size 1 | 60 µl |
| Size 2 | 120 µl |
| Size 3 | 200 µl |
| Form | Liquid |
| Tested Applications | WB |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-7 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O94905 |
| Gene ID | 11160 |
| NCBI Accession | NP_001003790.1 |
| Background | Antibody anti-ERLIN2 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
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ERLIN2 antibody
Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation(ERAD) of inositol 1,4,5-trisphosphate receptors(IP3Rs) such as ITPR1(PubMed:19240031, PubMed:17502376). Promotes sterol-accelerated ERAD of HMGCR probably implicating an AMFR/gp78-containing ubiquitin ligase complex(PubMed:21343306). Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. May promote ER retention of the SCAP-SREBF complex(PubMed:24217618).
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ER Lipid Raft Associated 2 (ERLIN2) Antibody
ERLIN2 Antibody is a Rabbit Polyclonal Antibody against ERLIN2.
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ER Lipid Raft Associated 2 (ERLIN2) Antibody
Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1, 4, 5-trisphosphate receptors (IP3Rs). Also involved in ITPR1 degradation by the ERAD pathway.
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