ER Degradation Enhancer, Mannosidase alpha-Like 2 (EDEM2) Antibody
221€ (50 µg)
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935106861
info@markelab.com
name
ER Degradation Enhancer, Mannosidase alpha-Like 2 (EDEM2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx322885
tested applications
ELISA, IHC
Description
EDEM2 Antibody is a Rabbit Polyclonal against EDEM2.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | ER Degradation Enhancer, Mannosidase alpha-Like 2 (EDEM2) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1/10000, IHC: 1/100 - 1/300. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, IHC |
| Buffer | PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9BV94 |
| Gene ID | 55741 |
| Background | Antibody anti-EDEM2 |
| Status | RUO |
Descripción
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EDEM2 antibody
Initiates the endoplasmic reticulum-associated degradation(ERAD) that targets misfolded glycoproteins for degradation in an N-glycan-dependent manner. Catalyzes the first mannose trimming step, from Man9GlcNAc2 to Man8GlcNAc2(PubMed:25092655). Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle.
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ER Degradation Enhancer, Mannosidase Alpha-Like 2 (EDEM2) Antibody
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ER Degradation Enhancer, Mannosidase Alpha-Like 2 (EDEM2) Antibody
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