EDEM2 antibody

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935106861
info@markelab.com
name
EDEM2 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab02632
tested applications
ELISA, WB

Description

Initiates the endoplasmic reticulum-associated degradation(ERAD) that targets misfolded glycoproteins for degradation in an N-glycan-dependent manner. Catalyzes the first mannose trimming step, from Man9GlcNAc2 to Man8GlcNAc2(PubMed:25092655). Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle.

Documents del producto

Instrucciones
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Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
ER degradation enhancer, mannosidase alpha-like 2 (EDEM2)
Host
Rabbit
Reactivity
Human, Mouse, Rat
Recommended Dilution
WB: 1:500-1:2000
Clonality
polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
60-65 kDa
Purity
≥95% as determined by SDS-PAGE
Purification
Immunogen affinity purified
Size 1
100µg
Form
liquid
Tested Applications
ELISA, WB
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
UniProt ID
Q9BV94
Gene ID
55741
Alias
ER degradation-enhancing alpha-mannosidase-like protein 2,EDEM2,C20orf31,C20orf49
Background
Antibody anti-EDEM2
Status
RUO
Note
Mol. Weight 60-65 kDa

Descripción

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