EDEM2 antibody

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935106861
info@markelab.com
name
EDEM2 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab02632
tested applications
ELISA, WB
Description
Initiates the endoplasmic reticulum-associated degradation(ERAD) that targets misfolded glycoproteins for degradation in an N-glycan-dependent manner. Catalyzes the first mannose trimming step, from Man9GlcNAc2 to Man8GlcNAc2(PubMed:25092655). Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | ER degradation enhancer, mannosidase alpha-like 2 (EDEM2) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 60-65 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9BV94 |
| Gene ID | 55741 |
| Alias | ER degradation-enhancing alpha-mannosidase-like protein 2,EDEM2,C20orf31,C20orf49 |
| Background | Antibody anti-EDEM2 |
| Status | RUO |
| Note | Mol. Weight 60-65 kDa |
Descripción
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