ER Degradation Enhancer, Mannosidase Alpha-Like 2 (EDEM2) Antibody
377€ (100 µg)
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935106861
info@markelab.com
name
ER Degradation Enhancer, Mannosidase Alpha-Like 2 (EDEM2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx232632
tested applications
ELISA, WB
Description
EDEM2 Antibody is a Rabbit Polyclonal against EDEM2.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: ER Degradation Enhancer, Mannosidase Alpha-Like 2 (EDEM2) Immunogen: ER degradation enhancer, mannosidase alpha-like 2 |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Assay Type | Concentration: 2 mg/ml |
| Recommended Dilution | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Observed MW: 60-65 kDa |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9BV94 |
| Gene ID | 55741 |
| OMIM | 610302 |
| Background | Antibody anti-EDEM2 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
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Initiates the endoplasmic reticulum-associated degradation(ERAD) that targets misfolded glycoproteins for degradation in an N-glycan-dependent manner. Catalyzes the first mannose trimming step, from Man9GlcNAc2 to Man8GlcNAc2(PubMed:25092655). Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle.
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ER Degradation Enhancer, Mannosidase Alpha-Like 2 (EDEM2) Antibody
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