Glycerophosphocholine Cholinephosphodiesterase ENPP6 (ENPP6) Antibody

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357.5€ (100 µg)

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935106861
info@markelab.com
name
Glycerophosphocholine Cholinephosphodiesterase ENPP6 (ENPP6) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx036797
tested applications
ELISA, WB, IHC

Description

Rabbit Polyclonal against the ENPP6 protein.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
Glycerophosphocholine Cholinephosphodiesterase ENPP6 (ENPP6)
Host
Rabbit
Reactivity
Human
Recommended Dilution
ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000, IHC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Purified by antigen affinity column chromatography.
Size 1
100 µg
Size 2
1 mg
Form
Lyophilized
Tested Applications
ELISA, WB, IHC
Buffer
Prior to lyophilization: 1% BSA and 0.02% NaN3.
Availability
Shipped within 7-15 working days.
Storage
Store at -20 °C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q6UWR7
Gene ID
133121
OMIM
616983
Background
Antibody anti-ENPP6
Status
RUO
Note
Concentration: Lyophilized form: Not applicable.  After reconstitution: 1 mg/ml. -

Descripción

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Choline-specific glycerophosphodiester phosphodiesterase. The preferred substrate may be lysosphingomyelin(By similarity). Hydrolyzes lysophosphatidylcholine(LPC) to form monoacylglycerol and phosphorylcholine but not lysophosphatidic acid, showing it has a lysophospholipase C activity. Has a preference for LPC with short(12:0 and 14:0) or polyunsaturated(18:2 and 20:4) fatty acids. Also hydrolyzes glycerophosphorylcholine and sphingosylphosphorylcholine efficiently. Hydrolyzes the classical substrate for phospholipase C, p-nitrophenyl phosphorylcholine in vitro, while it does not hydrolyze the classical nucleotide phosphodiesterase substrate, p-nitrophenyl thymidine 5'-monophosphate. Does not hydrolyze diacyl phospholipids such as phosphatidylethanolamine, phosphatidylinositol, phosphatidylserine, phosphatidylglycerol and phosphatidic acid.

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