ENPP6 antibody
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Description
Choline-specific glycerophosphodiester phosphodiesterase. The preferred substrate may be lysosphingomyelin(By similarity). Hydrolyzes lysophosphatidylcholine(LPC) to form monoacylglycerol and phosphorylcholine but not lysophosphatidic acid, showing it has a lysophospholipase C activity. Has a preference for LPC with short(12:0 and 14:0) or polyunsaturated(18:2 and 20:4) fatty acids. Also hydrolyzes glycerophosphorylcholine and sphingosylphosphorylcholine efficiently. Hydrolyzes the classical substrate for phospholipase C, p-nitrophenyl phosphorylcholine in vitro, while it does not hydrolyze the classical nucleotide phosphodiesterase substrate, p-nitrophenyl thymidine 5'-monophosphate. Does not hydrolyze diacyl phospholipids such as phosphatidylethanolamine, phosphatidylinositol, phosphatidylserine, phosphatidylglycerol and phosphatidic acid.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | ectonucleotide pyrophosphatase/phosphodiesterase 6 (ENPP6) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 50 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q6UWR7 |
| Gene ID | 133121 |
| Alias | Glycerophosphocholine cholinephosphodiesterase ENPP6 (GPC-Cpde),Choline-specific glycerophosphodiester phosphodiesterase,Ectonucleotide pyrophosphatase/phosphodiesterase family member 6 (E-NPP 6, NPP-6),ENPP6 |
| Background | Antibody anti-ENPP6 |
| Status | RUO |
| Note | Mol. Weight 50 kDa |
Descripción
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ENPP6 antibody
Choline-specific glycerophosphodiester phosphodiesterase. The preferred substrate may be lysosphingomyelin(By similarity). Hydrolyzes lysophosphatidylcholine(LPC) to form monoacylglycerol and phosphorylcholine but not lysophosphatidic acid, showing it has a lysophospholipase C activity. Has a preference for LPC with short(12:0 and 14:0) or polyunsaturated(18:2 and 20:4) fatty acids. Also hydrolyzes glycerophosphorylcholine and sphingosylphosphorylcholine efficiently. Hydrolyzes the classical substrate for phospholipase C, p-nitrophenyl phosphorylcholine in vitro, while it does not hydrolyze the classical nucleotide phosphodiesterase substrate, p-nitrophenyl thymidine 5'-monophosphate. Does not hydrolyze diacyl phospholipids such as phosphatidylethanolamine, phosphatidylinositol, phosphatidylserine, phosphatidylglycerol and phosphatidic acid.
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Glycerophosphocholine Cholinephosphodiesterase ENPP6 (ENPP6) Antibody
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