E3 Ubiquitin-Protein Ligase RLIM (RLIM) Antibody

Product Graph
260€ (50 µg)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
E3 Ubiquitin-Protein Ligase RLIM (RLIM) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx457259
tested applications
ELISA, WB, IHC

Description

E3 Ubiquitin-Protein Ligase RLIM (RLIM) Antibody is a Rabbit polyclonal antibody for the detection of Human E3 Ubiquitin-Protein Ligase RLIM (RLIM).

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
E3 Ubiquitin-Protein Ligase RLIM (RLIM)
Host
Rabbit
Reactivity
Human
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Size 1
50 µg
Size 2
100 µg
Form
Liquid
Tested Applications
ELISA, WB, IHC
Buffer
0.01 M PBS, pH 7.4, 50% glycerol, 0.05% Proclin-300.
Availability
Shipped within 5-12 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q9NVW2
Gene ID
51132
NCBI Accession
NP_057204.2
Background
Antibody anti-RLIM
Status
RUO

Descripción

Related Products

FNab07320

RLIM antibody

E3 ubiquitin-protein ligase. Acts as a negative coregulator for LIM homeodomain transcription factors by mediating the ubiquitination and subsequent degradation of LIM cofactors LDB1 and LDB2 and by mediating the recruitment the SIN3a/histone deacetylase corepressor complex. Ubiquitination and degradation of LIM cofactors LDB1 and LDB2 allows DNA-bound LIM homeodomain transcription factors to interact with other protein partners such as RLIM. Plays a role in telomere length-mediated growth suppression by mediating the ubiquitination and degradation of TERF1. By targeting ZFP42 for degradation, acts as an activator of random inactivation of X chromosome in the embryo, a stochastic process in which one X chromosome is inactivated to minimize sex-related dosage differences of X-encoded genes in somatic cells of female placental mammals.

Ver Producto
P9121

Recombinant Human RLIM

Ver Producto
abx115301

Ring Finger Protein, Lim Domain Interacting (RLIM) Antibody

Ring Finger Protein, Lim Domain Interacting Antibody is a Rabbit Polyclonal antibody against Ring Finger Protein, Lim Domain Interacting.

Ver Producto