Dynein Light Chain LC8-Type 2 (DYNLL2) Antibody (FITC)
169€ (20 µg)
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Name
Dynein Light Chain LC8-Type 2 (DYNLL2) Antibody (FITC)
Category
Primary Antibodies
Provider
Abbexa
Reference
abx309354
Description
DYNLL2 Antibody (FITC) is a Rabbit Polyclonal against DYNLL2 conjugated to FITC.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Dynein Light Chain LC8-Type 2 (DYNLL2) Immunogen: Recombinant human Dynein light chain 2, cytoplasmic protein (1-89AA). |
| Host | Rabbit |
| Reactivity | Human |
| Detection Method | Laser Line: 488 Excitation/Emission: 499/515 |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | FITC |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q96FJ2 |
| Gene ID | 140735 |
| OMIM | 608942 |
| Alias | DLC2,DNCL1B,Dlc2,RSPH22,8 kDa dynein light chain b,DLC8b,Dynein light chain LC8-type 2 |
| Background | Antibody anti-DYNLL2 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
Dynein light chain 2, cytoplasmic (DYNLL2) is a protein that plays a vital role in regulating the function of the dynein motor complex, a key molecular motor involved in the transport of cellular cargo along microtubules in the cytoplasm DYNLL2, as a light chain component, helps stabilize the dynein complex and is involved in intracellular processes such as vesicle trafficking, organelle positioning, and mitotic spindle formation During cell division, DYNLL2 is required for the proper organization of the mitotic spindle and the movement of chromosomes, ensuring accurate cell division Additionally, DYNLL2 is implicated in regulating the actin cytoskeleton and modulating cellular signaling pathways, such as those involved in apoptosis and stress responses Dysregulation of DYNLL2 has been linked to various diseases, including neurodegenerative disorders, where impaired intracellular transport and organelle dysfunction contribute to neuronal damage DYNLL2’s essential roles in intracellular transport, cell cycle regulation, and cellular signaling make it crucial for maintaining normal cellular function and homeostasis
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