Dynein Light Chain 1, Cytoplasmic (DYNLL1) Antibody
169€ (20 µg)
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Name
Dynein Light Chain 1, Cytoplasmic (DYNLL1) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx109742
Tested Applications
ELISA, WB, IHC, IF/ICC
Description
Dynein Light Chain 1, Cytoplasmic Antibody is a Rabbit Polyclonal antibody against Dynein Light Chain 1, Cytoplasmic.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Dynein Light Chain 1, Cytoplasmic (DYNLL1) Immunogen: Recombinant human Dynein light chain 1, cytoplasmic protein (1-89AA). |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/500 - 1/5000, IHC: 1/20 - 1/200, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P63167 |
| Gene ID | 8655 |
| OMIM | 601562 |
| Alias | DLC1,DLC8,DNCL1,DNCLC1,LC8,LC8a,PIN,hdlc1,8 kDa dynein light chain |
| Background | Antibody anti-DYNLL1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
Dynein light chain 1, cytoplasmic (DYNLL1) is a protein that plays a critical role in the regulation of motor protein activity, particularly the dynein motor complex, which is involved in intracellular transport and cell division DYNLL1 functions as part of the dynein complex by binding to the dynein intermediate and heavy chains, facilitating the movement of cellular cargo along microtubules in the cytoplasm This process is essential for the transport of vesicles, organelles, and protein complexes within the cell, and for maintaining the proper positioning of mitotic spindles during cell division DYNLL1 also has a role in regulating the actin cytoskeleton and modulating various signaling pathways, including those involved in apoptosis and stress responses Dysregulation of DYNLL1 has been linked to neurodegenerative diseases, where defective cellular transport and organelle dysfunction contribute to neuronal damage It is also implicated in cancer, where its interaction with key signaling pathways can influence tumor cell migration and metastasis DYNLL1’s essential functions in intracellular trafficking and cellular signaling underscore its importance in maintaining normal cellular function and tissue homeostasis
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