Dual Specificity Protein Kinase CLK2 (CLK2) Antibody

Product Graph
52€ (10 µg)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
Dual Specificity Protein Kinase CLK2 (CLK2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx013505
tested applications
ELISA, WB

Description

Rabbit polyclonal antibody against CLK2 protein. Immunogen region is N-terminal.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Dual Specificity Protein Kinase CLK2 (CLK2)
Host
Rabbit
Reactivity
Human, Mouse, Rat
Recommended Dilution
WB: 1/500 - 1/3000, ELISA: 1/20000. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen.
Size 1
10 µg
Size 2
100 µg
Size 3
200 µg
Size 4
300 µg
Size 5
1 mg
Form
Liquid
Tested Applications
ELISA, WB
Buffer
PBS (without Mg<sup>2+</sup> and Ca<sup>2+</sup>), pH 7.4, 150 mM NaCl, 0.02% sodium azide, 50% glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P49760
Gene ID
1196
OMIM
602989
Background
Antibody anti-CLK2
Status
RUO
Note
Concentration: 1 mg/ml -

Descripción

Related Products

FNab01766

CLK2 antibody

Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine-and arginine-rich(SR) proteins of the spliceosomal complex. May be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing and can cause redistribution of SR proteins from speckles to a diffuse nucleoplasmic distribution. Acts as a suppressor of hepatic gluconeogenesis and glucose output by repressing PPARGC1A transcriptional activity on gluconeogenic genes via its phosphorylation. Phosphorylates PPP2R5B thereby stimulating the assembly of PP2A phosphatase with the PPP2R5B-AKT1 complex leading to dephosphorylation of AKT1. Phosphorylates: PTPN1, SRSF1 and SRSF3. Regulates the alternative splicing of tissue factor(F3) pre-mRNA in endothelial cells.

Ver Producto
abx006043

Dual Specificity Protein Kinase CLK2 (CLK2) Antibody

CLK2 Antibody is a Rabbit Polyclonal Antibody against CLK2.

Ver Producto
abx013505

Dual Specificity Protein Kinase CLK2 (CLK2) Antibody

Rabbit polyclonal antibody against CLK2 protein. Immunogen region is N-terminal.

Ver Producto