Docking Protein 5 (DOK5) Antibody (HRP)
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935106861
info@markelab.com
Precio
162.5€ (20 µg)
Antibody anti-DOK5
proveedor
Abbexareference
abx108193Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
PolyclonalDescripción
Docking protein 5 Antibody (HRP) is a Rabbit Polyclonal antibody against Docking protein 5 conjugated to HRP.
Background
DOK5 is a member of the DOK family, functioning as an adaptor protein in signaling pathways downstream of RET and insulin receptors. It is expressed in skeletal muscle, heart, and nervous tissue, where it regulates processes like cell survival, differentiation, and metabolic signaling. DOK5 enhances insulin signaling by activating the MAPK/ERK pathway but does not influence the PI3K/Akt pathway. It is critical for neurite outgrowth and neuronal development, particularly in response to neurotrophic factors. Dysregulation of DOK5 contributes to insulin resistance and is implicated in neurological disorders, where it affects neuronal survival and axonal guidance.
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human
immunogen target
Docking Protein 5 (DOK5)
host
Rabbit
conjugation
HRP
form
Liquid
tested applications
ELISA
purity
> 95%
purification
Purified by Protein G.
buffer
0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol.
size 1
20 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
1 mg
storage
Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles.
or code
DOK5
dry ice
No
availability
Shipped within 5-10 working days.
alias
Downstream of tyrosine kinase 5,C20orf180,IRS-6,IRS6,Insulin receptor substrate 6
uniprot id
NCBI accession
NP_060901.2, NM_018431.4
note
This product is for research use only.
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