Docking Protein 5 (DOK5) Antibody
260€ (50 µl)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
Docking Protein 5 (DOK5) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx211476
Tested Applications
ELISA, IHC
Description
DOK5 Antibody is a Rabbit Polyclonal against DOK5.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Docking Protein 5 (DOK5) Immunogen: Fusion protein of human DOK5. |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | ELISA: 1/1000 - 1/2000, IHC: 1/10 - 1/50. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 50 µl |
| Size 2 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, IHC |
| Buffer | PBS, pH 7.4, containing 0.05% NaN3 and 40% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9P104 |
| Gene ID | 55816 |
| Alias | Downstream of tyrosine kinase 5,C20orf180,IRS-6,IRS6,Insulin receptor substrate 6 |
| Background | Antibody anti-DOK5 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
DOK5 is a member of the DOK family, functioning as an adaptor protein in signaling pathways downstream of RET and insulin receptors. It is expressed in skeletal muscle, heart, and nervous tissue, where it regulates processes like cell survival, differentiation, and metabolic signaling. DOK5 enhances insulin signaling by activating the MAPK/ERK pathway but does not influence the PI3K/Akt pathway. It is critical for neurite outgrowth and neuronal development, particularly in response to neurotrophic factors. Dysregulation of DOK5 contributes to insulin resistance and is implicated in neurological disorders, where it affects neuronal survival and axonal guidance.
Productos relacionados
Docking Protein 5 (DOK5) Antibody
Rabbit polyclonal antibody against DOK5 protein. Immunogen region is Internal.…
Ver producto Docking Protein 5 (DOK5) Antibody (Biotin)
Docking protein 5 Antibody (Biotin) is a Rabbit Polyclonal antibody against Docking protein 5 conjugated to Biotin.…
Ver producto
Docking Protein 5 (DOK5) Antibody (FITC)
Docking protein 5 Antibody (FITC) is a Rabbit Polyclonal antibody against Docking protein 5 conjugated to FITC.…
Ver producto