DNA Repair Protein Complementing XP-A Cells (XPA) Antibody
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
XPA Antibody is a Rabbit Polyclonal antibody against XPA. This gene encodes a zinc finger protein involved in DNA excision repair. The encoded protein is part of the NER (nucleotide excision repair) complext which is responsible for repair of UV radiation-induced photoproducts and DNA adducts induced by chemical carcinogens. Mutations in this gene are associated with xeroderma pigmentosum complementation group A. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2009].
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | DNA Repair Protein Complementing XP-A Cells (XPA) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | ELISA: 1 µg/ml, WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 20 µl |
| Size 2 | 100 µl |
| Size 3 | 2 × 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IF/ICC |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P23025 |
| Gene ID | 7507 |
| NCBI Accession | NP_000371.1 |
| Background | Antibody anti-XPA |
| Status | RUO |
| Note | Concentration: > 0.2 mg/ml - |
Descripción
Related Products
XPA antibody
Involved in DNA excision repair. Initiates repair by binding to damaged sites with various affinities, depending on the photoproduct and the transcriptional state of the region. Required for UV-induced CHEK1 phosphorylation and the recruitment of CEP164 to cyclobutane pyrimidine dimmers(CPD), sites of DNA damage after UV irradiation.
Ver Producto
DNA Repair Protein Complementing XP-A Cells (XPA) Antibody
XPA Antibody is a Rabbit Polyclonal antibody against XPA. This gene encodes a zinc finger protein involved in DNA excision repair. The encoded protein is part of the NER (nucleotide excision repair) complext which is responsible for repair of UV radiation-induced photoproducts and DNA adducts induced by chemical carcinogens. Mutations in this gene are associated with xeroderma pigmentosum complementation group A. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2009].
Ver Producto
DNA Repair Protein Complementing XP-A Cells (XPA) Antibody
Rabbit polyclonal antibody against XPA protein. Immunogen region is C-terminal.
Ver Producto