XPA antibody
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Description
Involved in DNA excision repair. Initiates repair by binding to damaged sites with various affinities, depending on the photoproduct and the transcriptional state of the region. Required for UV-induced CHEK1 phosphorylation and the recruitment of CEP164 to cyclobutane pyrimidine dimmers(CPD), sites of DNA damage after UV irradiation.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | xeroderma pigmentosum, complementation group A (XPA) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:200-1:2000; IF: 1:50-1:500 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 42 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P23025 |
| Gene ID | 7507 |
| Alias | DNA repair protein complementing XP-A cells,Xeroderma pigmentosum group A-complementing protein,XPA,XPAC |
| Background | Antibody anti-XPA |
| Status | RUO |
| Note | Mol. Weight 42 kDa |
Descripción
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XPA antibody
Involved in DNA excision repair. Initiates repair by binding to damaged sites with various affinities, depending on the photoproduct and the transcriptional state of the region. Required for UV-induced CHEK1 phosphorylation and the recruitment of CEP164 to cyclobutane pyrimidine dimmers(CPD), sites of DNA damage after UV irradiation.
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