DNA-(Apurinic Or Apyrimidinic Site) Lyase (APEX1) Antibody
195€ (20 µl)
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Name
DNA-(Apurinic Or Apyrimidinic Site) Lyase (APEX1) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx001032
Tested Applications
ELISA, WB, IF/ICC
Description
APEX1 Antibody is a Rabbit Polyclonal antibody against APEX1. Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: DNA-(Apurinic Or Apyrimidinic Site) Lyase (APEX1) Immunogen: Recombinant protein corresponding to APEX1. The exact sequence is proprietary. |
| Host | Rabbit |
| Reactivity | Human |
| Assay Type | Concentration: > 0.2 mg/ml |
| Recommended Dilution | ELISA: 1 µg/ml, WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Calculated MW: 36 kDa Observed MW: 39 kDa |
| Purification | Purified by affinity chromatography. |
| Size 1 | 20 µl |
| Size 2 | 100 µl |
| Size 3 | 2 × 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IF/ICC |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P27695 |
| Gene ID | 318 |
| NCBI Accession | NP_542380.1 |
| Alias | APEX1,APE,APE1,APEX,APX |
| Background | Antibody anti-APEX1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
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