Disintegrin And Metalloproteinase Domain-Containing Protein 21 (ADAM21) Antibody

357.5€ (100 µg)
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935106861
info@markelab.com
name
Disintegrin And Metalloproteinase Domain-Containing Protein 21 (ADAM21) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx038106
tested applications
ELISA, WB
Description
Rabbit Polyclonal against the ADAM21 protein.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Primary Antibodies |
Immunogen Target | Disintegrin And Metalloproteinase Domain-Containing Protein 21 (ADAM21) |
Host | Rabbit |
Reactivity | Human |
Recommended Dilution | ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Purification | Purified by Protein A/G column chromatography. |
Size 1 | 100 µg |
Size 2 | 1 mg |
Form | Lyophilized |
Tested Applications | ELISA, WB |
Buffer | Prior to lyophilization: 0.02% NaN3. |
Availability | Shipped within 7-15 working days. |
Storage | Store at -20 °C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
Alias | ADAM31, EC 3.4.24,A Disintegrin And Metalloproteinase Domain 21,adam-21 |
Background | Antibody anti-ADAM21 |
Status | RUO |
Note | Concentration: Lyophilized form: Not applicable. After reconstitution: 1 mg/ml. - |
Descripción
ADAM21 (A Disintegrin And Metalloproteinase domain-containing protein 21) is a member of the ADAM (A Disintegrin And Metalloproteinase) family. This family is involved in various biological processes such as cell adhesion, migration, proteolysis, and signaling. ADAM proteins are characterized by their multidomain structure, which includes a metalloproteinase domain responsible for proteolytic activity, a disintegrin domain involved in cell adhesion and signaling, a cysteine-rich domain, an EGF-like domain, a transmembrane domain, and a cytoplasmic tail. ADAM21, specifically, is believed to play a role in fertilization. Studies have suggested its presence in sperm cells and involvement in sperm-egg interactions during fertilization. However, compared to other members of the ADAM family, relatively less is known about ADAM21, and further research is needed to fully understand its functions and mechanisms of action.
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