ADAM Metallopeptidase Domain 21 (ADAM21) Antibody
260€ (50 µl)
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Name
ADAM Metallopeptidase Domain 21 (ADAM21) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx339153
Tested Applications
ELISA, IHC
Description
ADAM21 Antibody is a Rabbit Polyclonal against ADAM21.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: ADAM Metallopeptidase Domain 21 (ADAM21) Immunogen: Fusion protein of human ADAM21. |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1/1000 - 1/2000, IHC: 1/15 - 1/50. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 50 µl |
| Size 2 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, IHC |
| Buffer | PBS, pH 7.4, containing 0.05% NaN3 and 40% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9UKJ8 |
| Gene ID | 8747 |
| Alias | ADAM31, EC 3.4.24,A Disintegrin And Metalloproteinase Domain 21,adam-21 |
| Background | Antibody anti-ADAM21 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
ADAM21 (A Disintegrin And Metalloproteinase domain-containing protein 21) is a member of the ADAM (A Disintegrin And Metalloproteinase) family. This family is involved in various biological processes such as cell adhesion, migration, proteolysis, and signaling. ADAM proteins are characterized by their multidomain structure, which includes a metalloproteinase domain responsible for proteolytic activity, a disintegrin domain involved in cell adhesion and signaling, a cysteine-rich domain, an EGF-like domain, a transmembrane domain, and a cytoplasmic tail. ADAM21, specifically, is believed to play a role in fertilization. Studies have suggested its presence in sperm cells and involvement in sperm-egg interactions during fertilization. However, compared to other members of the ADAM family, relatively less is known about ADAM21, and further research is needed to fully understand its functions and mechanisms of action.
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