Cytoplasmic Protein NCK1 (NCK1) Protein
234€ (5 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
Cytoplasmic Protein NCK1 (NCK1) Protein
Category
Proteins and Peptides
Provider
Abbexa
Reference
abx260606
Tested Applications
SDS-PAGE
Description
NCK1 is a recombinant protein.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Proteins and Peptides |
| Immunogen Target | NCK1 |
| Assay Type | Activity: Not tested |
| Conjugation | Unconjugated |
| Expression | Recombinant |
| Purity | > 90% (SDS-PAGE) |
| Size 1 | 5 µg |
| Size 2 | 25 µg |
| Size 3 | 1 mg |
| Form | Liquid |
| Tested Applications | SDS-PAGE |
| Availability | Shipped within 5-10 working days. |
| Dry Ice | No |
| UniProt ID | P16333 |
| Alias | NCK1, NCK, NCKalpha, nck-1, NCK adaptor protein 1 |
| Background | Protein NCK1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
NCK1 is a cytoplasmic adaptor protein containing three SH3 domains and one SH2 domain, which allows it to mediate interactions between receptor tyrosine kinases (RTKs) and downstream effectors in signaling pathways. NCK1 is involved in actin cytoskeleton reorganization, cell motility, and immune synapse formation by linking signaling proteins such as WASP, WAVE, and PAK1. It plays key roles in processes like cell migration, proliferation, and T-cell activation. NCK1 is highly expressed in various tissues and regulates growth factor receptor signaling, including pathways like MAPK/ERK and PI3K. Dysregulation of NCK1 is associated with cancer progression, metastasis, and immune system dysfunction. Knockout studies show defects in actin dynamics, impaired cell movement, and reduced T-cell activation, highlighting its importance in cytoskeletal signaling and cellular communication.
Productos relacionados
Cytoplasmic Protein NCK1 (NCK1) Antibody
NCK1 Antibody is a Rabbit Polyclonal antibody against NCK1. The protein encoded by this gene is one of the signaling and…
Ver producto
Cytoplasmic Protein NCK1 (NCK1) Antibody
The protein encoded by this gene is one of the signaling and transforming proteins containing Src homology 2 and 3 (SH2 …
Ver producto
Cytoplasmic Protein NCK1 (NCK1) Antibody
The protein encoded by this gene is one of the signaling and transforming proteins containing Src homology 2 and 3 (SH2 …
Ver producto