Cyclin Dependent Kinase Inhibitor 1C (CDKN1C) Antibody
383.5€ (100 µl)
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935106861
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name
Cyclin Dependent Kinase Inhibitor 1C (CDKN1C) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx010611
tested applications
ELISA
Description
Cyclin-dependent kinase inhibitor 1C is a tight-binding inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations of CDKN1C are implicated in sporadic cancers and Beckwith-Wiedemann syndorome suggesting that it is a tumor suppressor candidate.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Cyclin Dependent Kinase Inhibitor 1C (CDKN1C) |
| Host | Mouse |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1/10000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG1 |
| Purification | Unpurified ascites. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P49918 |
| Gene ID | 1028 |
| OMIM | 130650 |
| Background | Antibody anti-CDKN1C |
| Status | RUO |
| Note | Concentration: Not determined. - |
Descripción
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Cyclin Dependent Kinase Inhibitor 1C (CDKN1C) Antibody
CDKN1C Antibody is a Rabbit Polyclonal antibody against CDKN1C. This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene.
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