Cyclin Dependent Kinase Inhibitor 1C (CDKN1C) Antibody
312€ (60 µl)
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935106861
info@markelab.com
name
Cyclin Dependent Kinase Inhibitor 1C (CDKN1C) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx001677
tested applications
WB
Description
CDKN1C Antibody is a Rabbit Polyclonal antibody against CDKN1C. This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Cyclin Dependent Kinase Inhibitor 1C (CDKN1C) |
| Host | Rabbit |
| Reactivity | Mouse, Rat |
| Recommended Dilution | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 60 µl |
| Size 2 | 120 µl |
| Size 3 | 200 µl |
| Form | Liquid |
| Tested Applications | WB |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P49918 |
| Gene ID | 1028 |
| NCBI Accession | NP_000067.1 |
| Background | Antibody anti-CDKN1C |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
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Cyclin Dependent Kinase Inhibitor 1C (CDKN1C) Antibody
CDKN1C Antibody is a Rabbit Polyclonal antibody against CDKN1C. This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene.
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