Crk-Like Protein (CRKL) Cell ELISA Kit
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Description
CrkL Cell ELISA Kit is a cell-based ELISA Kit. Cells to be assayed should be seeded onto a clear flat bottom 96 well plate, using poly-L-lysine for non-adherent cells. Cells should be grown to 75-90% confluence and treated prior to carrying out the ELISA.
Documents del producto
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Crk-Like Protein (CRKL) |
| Reactivity | Human, Mouse, Rat |
| Detection Method | Colorimetric |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Tested Applications | ELISA |
| Availability | Shipped within 1-2 weeks. The validity for this kit is at least 6 months |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | P46109 |
| Gene ID | 1399 |
| OMIM | 602007 |
| Alias | CRK like proto-oncogene, crk-like protein |
| Background | Elisa kits for CRKL |
| Status | RUO |
| Note | Validity: 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
Crk-like protein (CRKL) is another adaptor protein that is structurally similar to CRK but has its own unique functions in cellular signaling. Like CRK, CRKL contains SH2 and SH3 domains, enabling it to interact with a variety of signaling molecules involved in cellular growth, survival, and migration. CRKL is a key component of signaling pathways activated by various RTKs, including those involved in cell differentiation and cytoskeletal remodeling. It plays an important role in cellular responses to growth factors, such as epidermal growth factor (EGF), and is implicated in the regulation of immune cell function. Dysregulation of CRKL has been linked to certain cancers and other diseases where altered cellular signaling occurs.
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