Crk-Like Protein (CRKL) Antibody (FITC)

Este producto es parte de CRKL-Crk-like protein
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169€ (20 µg)

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935106861
info@markelab.com
name
Crk-Like Protein (CRKL) Antibody (FITC)
category
Primary Antibodies
provider
Abbexa
reference
abx314805

Description

CRKL Antibody (FITC) is a Rabbit Polyclonal against CRKL conjugated to FITC.

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryPrimary Antibodies
Immunogen TargetCrk-Like Protein (CRKL)
HostRabbit
ReactivityHuman
Recommended DilutionOptimal dilutions/concentrations should be determined by the end user.
ClonalityPolyclonal
ConjugationFITC
IsotypeIgG
Purity> 95%
PurificationPurified by Protein G.
Size 120 µg
Size 250 µg
Size 3100 µg
Size 4200 µg
Size 51 mg
FormLiquid
Buffer0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol.
AvailabilityShipped within 5-10 working days.
StorageAliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles.
Dry IceNo
UniProt IDP46109
Gene ID1399
OMIM602007
AliasCRK like proto-oncogene, crk-like protein
BackgroundAntibody anti-CRKL
StatusRUO

Descripción

Crk-like protein (CRKL) is another adaptor protein that is structurally similar to CRK but has its own unique functions in cellular signaling. Like CRK, CRKL contains SH2 and SH3 domains, enabling it to interact with a variety of signaling molecules involved in cellular growth, survival, and migration. CRKL is a key component of signaling pathways activated by various RTKs, including those involved in cell differentiation and cytoskeletal remodeling. It plays an important role in cellular responses to growth factors, such as epidermal growth factor (EGF), and is implicated in the regulation of immune cell function. Dysregulation of CRKL has been linked to certain cancers and other diseases where altered cellular signaling occurs.

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