Coronin 2B (CORO2B) Antibody

Este producto es parte de CORO - Coronin
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292.5€ (80 µl)

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935106861
info@markelab.com
name
Coronin 2B (CORO2B) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx030151
tested applications
ELISA, WB

Description

CORO2B may play a role in the reorganization of neuronal actin structure.

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryPrimary Antibodies
Immunogen TargetCoronin 2B (CORO2B)
HostRabbit
ReactivityHuman
Recommended DilutionWB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
ClonalityPolyclonal
ConjugationUnconjugated
IsotypeIgG
PurificationPurified through a protein A column, followed by peptide affinity purification.
Size 180 µl
Size 2400 µl
FormLiquid
Tested ApplicationsELISA, WB
BufferPBS containing 0.09% sodium azide.
AvailabilityShipped within 5-10 working days.
StorageAliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry IceNo
UniProt IDQ9UQ03
AliasIR10,WDR2,CLIPINB,WD repeat-containing protein 2,Coronin-2A
BackgroundAntibody anti-CORO2B
StatusRUO

Descripción

Coronin 2B (CORO2B) is another member of the coronin protein family, and it shares similarities with CORO2A in its role of regulating actin dynamics. CORO2B is particularly important in the context of immune cells, such as macrophages, where it helps in processes like phagocytosis, cell migration, and the maintenance of actin cytoskeleton integrity. It also contributes to the regulation of immune responses and is involved in signaling pathways that control the activity of immune cells. In addition to its role in immune function, CORO2B has also been found to influence cell signaling in other tissues, including neurons, where it impacts processes related to cell movement and plasticity. Dysregulation of CORO2B can lead to immune deficiencies and other pathologies related to actin regulation.

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