Coronin 1B (CORO1B) Antibody

Este producto es parte de CORO - Coronin
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292.5€ (80 µl)

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935106861
info@markelab.com
name
Coronin 1B (CORO1B) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx029901
tested applications
ELISA, WB

Description

Members of the coronin family, such as CORO1B, are WD repeat-containing actin-binding proteins that regulate cell motility (Cai et al., 2005 [PubMed 16027158]).

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryPrimary Antibodies
Immunogen TargetCoronin 1B (CORO1B)
HostRabbit
ReactivityHuman
Recommended DilutionWB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
ClonalityPolyclonal
ConjugationUnconjugated
IsotypeIgG
PurificationPurified through a protein A column, followed by peptide affinity purification.
Size 180 µl
Size 2400 µl
FormLiquid
Tested ApplicationsELISA, WB
BufferPBS containing 0.09% sodium azide.
AvailabilityShipped within 5-10 working days.
StorageAliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry IceNo
UniProt IDQ9BR76
Aliasp57,IMD8,TACO,CLABP,HCORO1,CLIPINA,CORO1,Tryptophan aspartate-containing coat protein (TACO),Coronin-like protein p57,Coronin-like protein A,Clipin-A,Coronin-1A
BackgroundAntibody anti-CORO1B
StatusRUO

Descripción

Coronin 1B (CORO1B) is another member of the coronin family, sharing functional similarities with other coronin proteins but also exhibiting unique features in different tissues. CORO1B is involved in regulating the dynamics of actin filaments within cells, particularly in the context of immune cells and neurons. It plays a key role in cellular processes such as migration, endocytosis, and phagocytosis, especially in macrophages. The protein also contributes to the stability of actin networks in immune responses, which is essential for effective immune surveillance and pathogen elimination. Additionally, CORO1B has been implicated in the regulation of synaptic function in neurons. Its dysregulation has been associated with disorders related to the immune system and neurodegeneration, emphasizing its importance in both immune function and neuronal activity.

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