Coronin 1A (CORO1A) Antibody (FITC)
169€ (20 µg)
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Name
Coronin 1A (CORO1A) Antibody (FITC)
Category
Primary Antibodies
Provider
Abbexa
Reference
abx314802
Description
CORO1A Antibody (FITC) is a Rabbit Polyclonal against CORO1A conjugated to FITC.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Coronin 1A (CORO1A) Immunogen: Recombinant Human Coronin-1A protein (363-432AA). |
| Host | Rabbit |
| Reactivity | Human |
| Detection Method | Laser Line: 488 Excitation/Emission: 499/515 |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | FITC |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P31146 |
| Gene ID | 11151 |
| OMIM | 605000 |
| Alias | p57,IMD8,TACO,CLABP,HCORO1,CLIPINA,CORO1,Tryptophan aspartate-containing coat protein (TACO),Coronin-like protein p57,Coronin-like protein A,Clipin-A,Coronin-1A |
| Background | Antibody anti-CORO1A |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
Coronin 1A (CORO1A) is a member of the coronin family of proteins, which play key roles in regulating actin dynamics and cellular processes such as endocytosis, cytokinesis, and immune cell signaling. CORO1A, specifically, is crucial for the function of immune cells, including T cells and macrophages. It is involved in controlling actin polymerization and organization, which affects cell motility, phagocytosis, and intracellular trafficking. CORO1A has been implicated in the regulation of both the immune response and synaptic plasticity in neurons. Mutations or dysregulation of CORO1A can lead to impaired immune function, and it has been linked to immune disorders, highlighting its role in maintaining cellular integrity and function during immune responses.
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