Coronin 1A (CORO1A) Antibody

Este producto es parte de CORO - Coronin
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884€ (1 ml)

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935106861
info@markelab.com
name
Coronin 1A (CORO1A) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx171927
tested applications
WB, IHC, IF/ICC

Description

This product is currently in development. The lead time for this product may be several months. Please contact us at

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryPrimary Antibodies
Immunogen TargetCoronin 1A (CORO1A)
HostMouse
ReactivityRat
Recommended DilutionWB: 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user.
ClonalityMonoclonal
ConjugationUnconjugated
PurificationPurified by Protein A and Protein G affinity chromatography.
Size 11 ml
FormLiquid
Tested ApplicationsWB, IHC, IF/ICC
Buffer0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol.
AvailabilityPlease enquire.
StorageAliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry IceNo
Aliasp57,IMD8,TACO,CLABP,HCORO1,CLIPINA,CORO1,Tryptophan aspartate-containing coat protein (TACO),Coronin-like protein p57,Coronin-like protein A,Clipin-A,Coronin-1A
BackgroundAntibody anti-CORO1A
StatusRUO

Descripción

Coronin 1A (CORO1A) is a member of the coronin family of proteins, which play key roles in regulating actin dynamics and cellular processes such as endocytosis, cytokinesis, and immune cell signaling. CORO1A, specifically, is crucial for the function of immune cells, including T cells and macrophages. It is involved in controlling actin polymerization and organization, which affects cell motility, phagocytosis, and intracellular trafficking. CORO1A has been implicated in the regulation of both the immune response and synaptic plasticity in neurons. Mutations or dysregulation of CORO1A can lead to impaired immune function, and it has been linked to immune disorders, highlighting its role in maintaining cellular integrity and function during immune responses.

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