Coronin 1A (CORO1A) Antibody

Este producto es parte de CORO - Coronin
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312€ (60 µl)

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935106861
info@markelab.com
name
Coronin 1A (CORO1A) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx123821
tested applications
WB, IHC

Description

CORO1A Antibody is a Rabbit Polyclonal Antibody against CORO1A.

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryPrimary Antibodies
Immunogen TargetCoronin 1A (CORO1A)
HostRabbit
ReactivityHuman, Mouse, Rat
Recommended DilutionWB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
ClonalityPolyclonal
ConjugationUnconjugated
IsotypeIgG
PurificationPurified by affinity chromatography.
Size 160 µl
Size 2120 µl
Size 3200 µl
FormLiquid
Tested ApplicationsWB, IHC
BufferPBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
AvailabilityShipped within 5-10 working days.
StorageAliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry IceNo
UniProt IDP31146
Gene ID11151
NCBI AccessionNP_001180262.1
Aliasp57,IMD8,TACO,CLABP,HCORO1,CLIPINA,CORO1,Tryptophan aspartate-containing coat protein (TACO),Coronin-like protein p57,Coronin-like protein A,Clipin-A,Coronin-1A
BackgroundAntibody anti-CORO1A
StatusRUO
NoteConcentration: 1 mg/ml -

Descripción

Coronin 1A (CORO1A) is a member of the coronin family of proteins, which play key roles in regulating actin dynamics and cellular processes such as endocytosis, cytokinesis, and immune cell signaling. CORO1A, specifically, is crucial for the function of immune cells, including T cells and macrophages. It is involved in controlling actin polymerization and organization, which affects cell motility, phagocytosis, and intracellular trafficking. CORO1A has been implicated in the regulation of both the immune response and synaptic plasticity in neurons. Mutations or dysregulation of CORO1A can lead to impaired immune function, and it has been linked to immune disorders, highlighting its role in maintaining cellular integrity and function during immune responses.

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