Coronin 1A (CORO1A) Antibody
312€ (60 µl)
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Name
Coronin 1A (CORO1A) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx123821
Tested Applications
WB, IHC
Description
CORO1A Antibody is a Rabbit Polyclonal Antibody against CORO1A.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Coronin 1A (CORO1A) Immunogen: Recombinant fusion protein corresponding to human CORO1A |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Assay Type | Concentration: 1 mg/ml |
| Recommended Dilution | WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Calculated MW: 51 kDa Observed MW: 51 kDa |
| Purification | Purified by affinity chromatography. |
| Size 1 | 60 µl |
| Size 2 | 120 µl |
| Size 3 | 200 µl |
| Form | Liquid |
| Tested Applications | WB, IHC |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P31146 |
| Gene ID | 11151 |
| NCBI Accession | NP_001180262.1 |
| Alias | p57,IMD8,TACO,CLABP,HCORO1,CLIPINA,CORO1,Tryptophan aspartate-containing coat protein (TACO),Coronin-like protein p57,Coronin-like protein A,Clipin-A,Coronin-1A |
| Background | Antibody anti-CORO1A |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
Coronin 1A (CORO1A) is a member of the coronin family of proteins, which play key roles in regulating actin dynamics and cellular processes such as endocytosis, cytokinesis, and immune cell signaling. CORO1A, specifically, is crucial for the function of immune cells, including T cells and macrophages. It is involved in controlling actin polymerization and organization, which affects cell motility, phagocytosis, and intracellular trafficking. CORO1A has been implicated in the regulation of both the immune response and synaptic plasticity in neurons. Mutations or dysregulation of CORO1A can lead to impaired immune function, and it has been linked to immune disorders, highlighting its role in maintaining cellular integrity and function during immune responses.
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