Collagen Type XVIII Alpha 1 (COL18A1) Antibody

Product Graph
52€ (10 µg)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
Collagen Type XVIII Alpha 1 (COL18A1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx013066
tested applications
ELISA, IHC

Description

Rabbit polyclonal antibody against COL18A1 protein. Immunogen region is C-terminal.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Collagen Type XVIII Alpha 1 (COL18A1)
Host
Rabbit
Reactivity
Human, Mouse
Recommended Dilution
IHC: 1/50 - 1/100, ELISA: 1/20000. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen.
Size 1
10 µg
Size 2
100 µg
Size 3
200 µg
Size 4
300 µg
Size 5
1 mg
Form
Liquid
Tested Applications
ELISA, IHC
Buffer
PBS (without Mg<sup>2+</sup> and Ca<sup>2+</sup>), pH 7.4, 150 mM NaCl, 0.02% sodium azide, 50% glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P39060
Background
Antibody anti-COL18A1
Status
RUO
Note
Concentration: 1 mg/ml -

Descripción

Related Products

FNab02762

COL18A1 antibody

Endostatin is a naturally-occurring 20-kDa C-terminal fragment derived from COL18A1(also named as KNO). It is reported to serve as an anti-angiogenic agent, similar to angiostatin and thrombospondin. It potently inhibits endothelial cell proliferation and inhibits endothelial cell angiogenesis by binding to the heparan sulfate proteoglycans involved in growth factor signaling. Endostatin is a broad spectrum angiogenesis inhibitor and may interfere with the pro-angiogenic action of growth factors such as basic fibroblast growth factor(bFGF/FGF-2) and vascular endothelial growth factor(VEGF).

Ver Producto
abx001439

Collagen Type XVIII Alpha 1 (COL18A1) Antibody

COL18A1 Antibody is a Rabbit Polyclonal antibody against COL18A1. This gene encodes the alpha chain of type XVIII collagen. This collagen is one of the multiplexins, extracellular matrix proteins that contain multiple triple-helix domains (collagenous domains) interrupted by non-collagenous domains. The proteolytically produced C-terminal fragment of type XVIII collagen is endostatin, a potent antiangiogenic protein. Mutations in this gene are associated with Knobloch syndrome. The main features of this syndrome involve retinal abnormalities, so type XVIII collagen may play an important role in retinal structure and in neural tube closure. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008].

Ver Producto
abx013066

Collagen Type XVIII Alpha 1 (COL18A1) Antibody

Rabbit polyclonal antibody against COL18A1 protein. Immunogen region is C-terminal.

Ver Producto