CMRF35-Like Molecule 6 (CD300C) Antibody
292.5€ (80 µl)
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935106861
info@markelab.com
name
CMRF35-Like Molecule 6 (CD300C) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx029106
tested applications
ELISA, WB
Description
The CMRF35 antigen, which was identified by reactivity with a monoclonal antibody, is present on monocytes, neutrophils, and some T and B lymphocytes (Jackson et al., 1992 [PubMed 1349532]).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | CMRF35-Like Molecule 6 (CD300C) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q08708 |
| Alias | CMRF35,CMRF35A,CMRF35A1,IGSF16,Immunoglobulin superfamily member 16,CD300 antigen-like family member C,CLM-6,CMRF35-like molecule 6 |
| Background | Antibody anti-CD300C |
| Status | RUO |
Descripción
CD300C, also known as immune receptor expressed by myeloid cells 2 (IREM-2), is a member of the CD300 family of immunoreceptors. The CD300 family, also known as the LMIR (leukocyte mono-immunoglobulin-like receptor) family, consists of several proteins that are predominantly expressed on the surface of myeloid and some lymphoid cells. These receptors are involved in the regulation of various immune responses, both activating and inhibitory, contributing to immune homeostasis and protection against pathogens. CD300C is encoded by the CD300C gene located on chromosome 17q25.1 in humans. This receptor is structurally similar to other members of the CD300 family, particularly CD300A, but it has distinct functional properties that are crucial for modulating immune cell activity.
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