Chicken Interleukin-6 (IL6) Protein
403€ (50 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Chicken Interleukin-6 (IL6) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx654056
tested applications
WB, SDS-PAGE
Description
Chicken Interleukin-6 (IL6) Protein is a recombinant Chicken protein expressed in E. coli.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Interleukin-6 (IL6) |
| Host | E. coli |
| Assay Type | Activity: Not tested Sequence Fragment: Gln87-Ala241 Tag: N-terminal His tag |
| Origin | Chicken |
| Conjugation | Unconjugated |
| Observed MW | Calculated MW: 21.6 kDa Observed MW: 22 kDa |
| Expression | Recombinant |
| Purity | > 90% |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Size 3 | 200 µg |
| Size 4 | 500 µg |
| Size 5 | 1 mg |
| Form | Lyophilized |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 5% Trehalose. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store lyophilized form at 2-8°C for up to 1 month. For longer periods, store lyophilized or liquid at -80°C. Avoid repeated freeze–thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q90YI0 |
| Alias | IL-6,BSF,HGF,HSF,IFNB2,CDF,B-cell stimulatory factor 2 |
| Background | Protein IL6 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. Concentration: Prior to lyophilization: 350 µg/ml |
Descripción
IL6 is a pleiotropic cytokine involved in regulating immune responses, inflammation, and hematopoiesis It is produced by macrophages, T cells, fibroblasts, and endothelial cells in response to infections, trauma, or tissue damage IL6 activates downstream signaling through its receptor, IL-6R, and the JAK/STAT3 pathway, driving acute-phase protein synthesis, such as CRP and fibrinogen, and promoting B cell differentiation into plasma cells Dysregulated IL6 expression is associated with chronic inflammation, autoimmune diseases like rheumatoid arthritis, and cancer progression, where it promotes tumor growth, survival, and angiogenesis IL6 also contributes to cytokine storm syndrome in conditions like COVID-19, where excessive IL6 leads to hyperinflammation and organ damage Targeting IL6 signaling with anti-IL6 therapies, such as tocilizumab, has shown efficacy in treating autoimmune diseases and cytokine-driven conditions
Related Products
APC Anti-Human IL-6(MQ2-13A5)
Ver Producto
Human HS-IL-6 (High sensitive Interleukin 6) high sensitive Accquant ELISA Kit
Ver Producto