Cell Death-Inducing DFFA-Like Effector B (CIDEB) Antibody
221€ (50 µg)
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935106861
info@markelab.com
name
Cell Death-Inducing DFFA-Like Effector B (CIDEB) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx326188
tested applications
ELISA, WB, IHC, IF/ICC
Description
CIDEB Antibody is a Rabbit Polyclonal against CIDEB.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Cell Death-Inducing DFFA-Like Effector B (CIDEB) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | ELISA: 1/40000, WB: 1/500 - 1/2000, IHC: 1/100 - 1/300, IF/ICC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Buffer | PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9UHD4 |
| Gene ID | 27141 |
| Alias | CIDEB, cell death-inducing DFFA-like effector b, cell death inducing DFFA like effector b,CIDE-B |
| Background | Antibody anti-CIDEB |
| Status | RUO |
Descripción
CIDEB is a protein critical for lipid metabolism and apoptosis, primarily expressed in the liver and associated with lipid droplet formation and triglyceride metabolism. It regulates lipid droplet growth and lipoprotein secretion, influencing hepatic lipid storage and export. CIDEB also participates in apoptosis by promoting the activation of caspase-dependent pathways, contributing to programmed cell death under stress conditions. Dysregulation of CIDEB has been implicated in liver diseases such as steatosis, non-alcoholic fatty liver disease (NAFLD), and liver fibrosis. Targeting CIDEB-mediated pathways is being explored for the treatment of metabolic liver diseases and conditions associated with altered lipid metabolism.
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